T cell subsets and functions in atherosclerosis

B Cell Subsets in Atherosclerosis

Atherosclerosis, the underlying cause of heart attacks and strokes, is a chronic inflammatory disease of the artery wall. Immune cells, including lymphocytes modulate atherosclerotic lesion development through interconnected mechanisms. Elegant studies over the past decades have begun to unravel a role for B cells in atherosclerosis. Recent findings provide evidence that B cell effects on ather...

Distinct Functions of Specialized Dendritic Cell Subsets in Atherosclerosis and the Road Ahead

Atherosclerotic vascular disease is modulated by immune mechanisms. Dendritic cells (DCs) and T cells are present within atherosclerotic lesions and function as central players in the initiation and modulation of adaptive immune responses. In previous years, we have studied the functional contribution of distinct DC subsets in disease development, namely, that of CCL17-expressing DCs as well as...

imbalance of t-cell subsets in iranian allergic rhinitis patients

r'iwenty-nine patients were studied to determine the number of cj).j+ tscell subsets in iranian allergic rhinitis patients. the result was compared with that a/twenty-four nonatopic controls. the number of11 and cds+t cell')and levels ofspeafic ige and /g(;4 against weed pollens were also studied the number of lymphocyte subset, tltat is, cd-/+ c/)29+and c1jf cj)451t cells were determined hy do...

The Immunomodulatory Effect of Cyclophosphamide on Regulation of T-Cell Subsets and Antigen Presenting Cells.

Modulation of CD4+ T Cell Subsets by Euphorbia microciadia and Euphorbia osyridea Plant Extracts

Background: Euphorbia plants are traditionally used in folk medicine for infections, inflammation, and cancer. Objectives: To investigate the effects of the butanolic extracts of Euphorbia micorociadia and Euphorbia osyridea on specific transcription factors and cytokines expression of T cell subsets. Methods: Activated mouse splenocytes were cultured in the presence of non-cytotoxic concentrat...